Prescription Reverse Engineering Technology Platform

Taking the polymer materials application library as the core and combining the reverse analysis technology of excipient types and models, accurately analyze the Q1 (qualitatively the same) and Q2 (quantitatively the same) of generic drugs, achieving efficient reproduction of prescriptions. Through reverse engineering methods, the formulation formulas of competing products can be quickly disassembled, the functions and proportion selection of key excipients can be analyzed, and the R&D cycle can be shortened. Meanwhile, the database accumulated by the platform covers the characteristics of various polymer materials, providing a scientific basis for the design of differentiated prescriptions, helping to break through the technical barriers of original research, and promoting the improvement and innovation of complex topical preparations (such as creams and gels).

In vitro evaluation technology platform

The platform integrates over ten Q3 (microstructure) characterization techniques, combines IVRT (in vitro release test) and the unique IVPT (in vitro permeation test), and builds a multi-dimensional in vitro evaluation system. By simulating the release and penetration behavior of drugs in the skin layer, the bioequivalence (BE) in vivo can be accurately predicted, reducing the cost and risk of clinical trials. In addition, the platform has established a quantitative correlation model between IVPT and BE, which can optimize prescription screening and guide process improvement, providing a scientific basis for the efficacy and safety of topical preparations, and accelerating the transformation process of products from research and development to market launch.